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Molecules are distinguished from ions by their lack of electrical charge. However, in quantum physics, organic chemistry, and biochemistry, the term molecule is … A context-dependent effect in cancer is common also to S-nitrosylation, with NO being considered a “Janus faced” molecule in tumorigenesis, due to its ability to both promote or inhibit cancer cell growth (Di Giacomo et al., 2012). From this angle, TRAP1 nitrosylation at Cys501 can play the role of … An estimated 15% of animals are venomous, with representatives spread across the majority of animal lineages. Animals use venoms for various purposes, such as prey capture and predator deterrence. Humans have always been fascinated by venomous animals in a Janus-faced way. On the one hand, humans have a deeply rooted fear of venomous animals.

Janus faced molecule

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Dynamics of raft molecules in the cell and artificial membranes: Approaches by pulse EPR spin labeling and single molecule optical microscopy. Biochim Biophys Acta 1610: 231–243. PubMed Google Scholar A Janus molecule (or Janus-faced molecule) is a molecule which can represent both beneficial and toxic effects. Examples are nitrous oxide [1] and cholesterol.

Janus may also refer to: Computing.

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The term Janus-faced molecule is derived from the ancient Roman god, Janus. Janus is depicted as having two faces; one facing the past and one facing the future. The Janus-faced role for CD44/PG in tumor progression is evident today, though CD44 was introduced early on as promoter of tumor metastasis or even as a metastasis gene (i.e. CD44v6).

Janus faced molecule

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[2] In the case of cholesterol, the property that makes cholesterol useful in cell membranes, namely its absolute insolubility in water, also makes it lethal. 2020-12-14 · Ly turned his focus to developing Janus PNAs. Named after the two-faced Roman god, Janus PNAs are double-sided, allowing them to bind to both strands of a DNA and RNA molecule. This hairpin structure in the Huntington’s RNA seemed that it would be a promising target for the Janus PNAs. 2018-9-20 · Ly turned his focus to developing Janus PNAs.

The term Janus-faced molecule is derived from  30 Jan 2013 Janus-faced microglia: beneficial and detrimental consequences of molecules involved in the phagocytosis of each target by microglia. Janus-faced bacterial regulation of epithelial cell death and survival: as a result of the absence or suppression of particular receptors or signaling molecules. 21 Jul 2020 This molecule proved to be high melting (208 °C dec) and an In order to explore the Janus face aspect of cyclohexane 14 further, 1H‐NMR  Reactive oxygen species (ROS) are highly reactive, unstable, and short-lived molecules that play a crucial role in both health and disease [5]. Physiological  (The limit of detection of free cholesterol molecules in solution is 10-8 M .) You may be surprised to learn that a molecule, β -cyclodextrin, built from glucose,  30 Oct 2017 As a cell surface molecule, PrPc has many interaction partners including transmembrane and secreted proteins. It also interact a variety of  18 Sep 2017 Cancer cell extravasation depends on adhesion molecules expressed in tumor cells and on the luminal surface of CECs.
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Janus faced molecule

However, in quantum physics, organic chemistry, and biochemistry, the term molecule is … A context-dependent effect in cancer is common also to S-nitrosylation, with NO being considered a “Janus faced” molecule in tumorigenesis, due to its ability to both promote or inhibit cancer cell growth (Di Giacomo et al., 2012).

2021-3-12 · Voltage-gated sodium ion channels (NaVs) are integral to both neuronal and muscular signaling and are a primary target for a number of proteinaceous and small molecule toxins. Included among these neurotoxins is veratridine (VTD), a C-nor-D homosteroidal alkaloid from the seeds of members of the Veratrum genus. VTD binds to NaV within the pore region, causing a hyperpolarizing … The Janus-faced role of external forces in mechanochemical disulfide bond cleavage, (2013),Nature Chemistry, DOI: 10.1038/nchem.1676 Journal information: Nature Chemistry Provided by Ruhr The guanine nucleotide exchange factor Tiam-1: a Janus-faced molecule in cellular signaling By Pomme Boissier and Uyen Huynh-Do No static citation data No static citation data Cite 2020-5-13 · Mont Janus, France; Science.
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In: Lajtha A., Reith M.E.A. (eds) Handbook of Neurochemistry and Molecular Neurobiology. Springer, Boston, MA. https://doi.org/10.1007/978-0-387-30380-2_7. First Online 01 January 2007; DOI https://doi.org/10.1007/978-0-387-30380-2_7 Two-Faced Molecule Slips between DNA Strands.


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26, 483-91, (2014). 30 Jan 2013 Janus-faced microglia: beneficial and detrimental consequences of molecules involved in the phagocytosis of each target by microglia. Janus-ansikte molekyl - Janus-faced molecule.